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Cell pathway engagement JAK

Portuguese translation: ensaios JAK de envolvimento em via celular

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Cell pathway engagement JAK
Portuguese translation:ensaios JAK de envolvimento em via celular
Entered by: Clauwolf

19:23 May 20, 2019
English to Portuguese translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: Cell pathway engagement JAK
Cell pathway engagement JAK assays:
Inhibition of the activity of JAK1 and JAK2 kinases in intact cells was quantified in antagonist mode using CellSensor® transcriptional reporter technology
Isadora Vital
United States
ensaios JAK de envolvimento em via celular
Explanation:
:) Pelo contexto
Selected response from:

Clauwolf
Local time: 02:12
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3(Ensaios / testes) com Janus quinases (JAK) sobre o papel das vias celulares
Andrea Pilenso
2 +1ensaios JAK de envolvimento em via celular
Clauwolf


  

Answers


38 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
cell pathway engagement jak
(Ensaios / testes) com Janus quinases (JAK) sobre o papel das vias celulares


Explanation:
Sugestão

file:///C:/Users/dell/Downloads/127-Texto%20Artigo-289-1-10-20170418.pdf

Os inibidores das Janus associated kinases são uma estratégia terapêutica recente direcionada para o tratamento de diversas patologias de natureza oncológica, inflamatória e autoimune.

As janus associated kinases (JAK) são uma família de enzimas envolvidas na transmissão de sinais de múltiplas citocinas, hormonas ou fatores de crescimento.

http://decs.bvs.br/cgi-bin/wxis1660.exe/decsserver/?IsisScri...

Janus Quinases
"Família de tirosina-quinases intracelulares que participam da cascata de sinalização de citocinas por associação com RECEPTORES DE CITOCINAS específicos. Atuam sobre os FATORES DE TRANSCRIÇÃO STAT na via de sinalização denominada como via JAK/STAT. O nome Janus quinase refere-se ao fato de que as proteínas apresentam dois domínios de tranferência fosfato."



Andrea Pilenso
Brazil
Local time: 02:12
Works in field
Native speaker of: Portuguese
PRO pts in category: 12
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45 mins   confidence: Answerer confidence 2/5Answerer confidence 2/5 peer agreement (net): +1
cell pathway engagement jak
ensaios JAK de envolvimento em via celular


Explanation:
:) Pelo contexto

Clauwolf
Local time: 02:12
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 59

Peer comments on this answer (and responses from the answerer)
agree  Margarida Ataide
5 days
  -> obrigado
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