gene silencing

Slovak translation: potlačenie transkripcie génov

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:gene silencing
Slovak translation:potlačenie transkripcie génov

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13:59 Feb 9, 2010
English to Slovak translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. biotech-info.net
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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potlačenie transkripcie génov
Definition:
Inhibícia transkripcie/translácie špecifických génov
Selected response from:

Dagmar Turčanová
Slovakia
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
4 +2potlačenie transkripcie génov
Dagmar Turčanová
4tlmenie génov, tlmenie aktivity génov
Igor Liba


  

Translations offered


21 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
tlmenie génov, tlmenie aktivity génov


Definition from Rezortná úloha výskumu a vývoja MP S:
Na reguláciu expresie myostatínu králika plánujeme použiť RNA interferenciu (RNAi) čo je evolučne vysoko konzervovaný proces postranskripčného tlmenia génov (PTGS) indukovaný dvojreťazcovou RNA (dsRNA).

Example sentence(s):
  • Následne výskumy zázvorového extraktu postúpili do fázy zisťovania inhibície – tlmenia niekoľkých génov zúčastňujúcich sa zápalovej reakcie. - Nutraceutika  
Igor Liba
Slovakia
Local time: 12:37
Native speaker of: Native in SlovakSlovak
PRO pts in category: 4
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28 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
potlačenie transkripcie génov


Definition from own experience or research:
Inhibícia transkripcie/translácie špecifických génov

Example sentence(s):
  • Zahrňuje potlačenie transkripcie génov (gene silencing) v závislosti na bunkovej diferenciácií - Jihočeská univerzita  

Explanation:
Uvádza sa aj „tíšenie génov“, „tlmenie génov“, „inhibícia transkripcie/translácie“
Dagmar Turčanová
Slovakia
Local time: 12:37
Native speaker of: Slovak
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Anton Šaliga
26 days

Yes  Maria Chmelarova
30 days
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