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chemokine receptor ligand (C-X-C motif) ligand 3

English translation: Yes, there is a difference

06:38 Jul 21, 2014
English language (monolingual) [PRO]
Law/Patents - Biology (-tech,-chem,micro-) / cytogenetics
English term or phrase: chemokine receptor ligand (C-X-C motif) ligand 3
Is there a difference between the 2 follwoing terms:
1- chemokine (C-X-C motif) ligand 3
2- chemokine receptor ligand (C-X-C motif) ligand 3

For first term, text reads:
*** Cells have increased expression of interleukin-8; reticulon 1; and chemokine (C-X-C motif) ligand 3, relative to that of a human cell which is a fibroblast, a mesenchymal stem cell, or an iliac crest bone marrow cell.

I simply translated it as CXCL3 Gene (protein-coding) or CXCL3 cytokine (a type of cytokines)

For second term, text says:
*** Cells have increased expression of interleukin-8; reticulon 1; and chemokine receptor ligand (C-X-C motif) ligand 3, relative to that of a human cell which is a fibroblast, a mesenchymal stem cell, or an iliac crest bone marrow cell.

It is little confusing. Can I translate it in the same way of FIRST term or they are different?
I think, the second term an be translated as "the ligand of the receptor of CXCL3 gene.
Please advise if this is a proper translation!

Thank you in advance.
FS
Fathy Shehatto
Egypt
Local time: 18:56
Selected answer:Yes, there is a difference
Explanation:
There are at least 46 chemokine ligands in humans. There are also 18 functionally signaling chemokine receptors (plus one, CXCR7, which has been recently reported as a potential chemokine receptor) and two 'decoy' or 'scavenger' receptors, DARC and D6, which are known to bind several chemokines but do not signal; their function may be to modulate inflammatory responses through their ability to remove chemokine ligands from inflammatory sites.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794421/

Selected response from:

acetran
Grading comment
4 KudoZ points were awarded for this answer



SUMMARY OF ALL EXPLANATIONS PROVIDED
3Yes, there is a difference
acetran


  

Answers


2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
chemokine receptor ligand (c-x-c motif) ligand 3
Yes, there is a difference


Explanation:
There are at least 46 chemokine ligands in humans. There are also 18 functionally signaling chemokine receptors (plus one, CXCR7, which has been recently reported as a potential chemokine receptor) and two 'decoy' or 'scavenger' receptors, DARC and D6, which are known to bind several chemokines but do not signal; their function may be to modulate inflammatory responses through their ability to remove chemokine ligands from inflammatory sites.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794421/



acetran
Native speaker of: Native in HindiHindi, Native in EnglishEnglish
PRO pts in category: 4
Notes to answerer
Asker: Good link! Thank you

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