Glossary entry

Spanish term or phrase:

frasco-ámpula

English translation:

vial

Added to glossary by liz askew
Mar 9, 2010 06:23
14 yrs ago
53 viewers *
Spanish term

frasco-ámpula

Spanish to English Medical Medical: Pharmaceuticals Drug Manufacturing
I'm translating a description of an injectable pharmaceutical product which discusses the drug's container.

The container is described as: "Frasco-ámpula vidrio ambar de 3 ml USP ..." The medication comes as a lyophilized powder which is mixed with water and administered intravenously.

This term is translated once in KudoZ in somebody's personal glossary, but I want to make sure that I'm using the correct translation, which is why I'm posting the question.

How do we say 'frasco-ámpula' in English?

Thanks for your help.
Proposed translations (English)
4 +1 vial
5 ampule bottle
5 ampoule
4 +1 sealed vial
5 vial
Change log

Mar 11, 2010 21:00: liz askew changed "Edited KOG entry" from "<a href="/profile/578038">Joseph Tein's</a> old entry - "frasco-ámpula"" to ""vial""

Discussion

Joseph Tein (asker) Mar 11, 2010:
This is the longest discussion that I have ever seen for a KudoZ question! And the winner is ... well ... ALL of you who have contributed. As David pointed out, this process is about helping people with their translation questions. As far as handing out the points, I think Liz's answer is correct and is the simplest and most direct solution. I like direct and simple. Thanks everybody for the great discussion.
David Brown Mar 10, 2010:
frasco-ampula I agree that simply putting "vial" would suffice. This is not a competition but an attempt to help the Asker with his translation. But do not get confused between these "all-glass" vials or ampoules and the bottle-type vial, which can both be clear glass or amber depending whether the contents are light-sensitive or not (the only reason I know for using amber vials).
Rita Tepper Mar 9, 2010:
Es una diferencia muy sutil Escribo en español para evitar errores. Las respuestas de Liz y David son correctas, todos los "vials" son "sealed vials" sino estarían contaminados. Yo voté por la de David porque contestó primero. Creo que anteponerle sealed o no ponerlo no cambia para nada el sentido. Pero esta discusión sirve para entender la diferencia entre "vial" y "ampoule". Nos enriqueció a todos.
liz askew Mar 9, 2010:
liz askew Mar 9, 2010:
Frankly, I am beginning to not really care which answer is chosen. If it were my translation I would put "vial". Based on all the sound evidence I have found. You may all put whatever you choose, but I have made up my own mind now. Kindly feel free to disagree with all my references, but I stand by them.
liz askew Mar 9, 2010:
Also, Joseph's context clearly states "frasco-ámpula......3mL" so is he wrong?
liz askew Mar 9, 2010:
PDF]
esquema de vacunacion oficio.cdr
- [ Translate this page ]
File Format: PDF/Adobe Acrobat - Quick View
Un frasco ámpula. Dosis única. Frasco ámpula 3ml administraci ón intramuscular. Penicilina benzat ínica combinada. Var ían desde dermatitis hasta el choque ...
www.cenavece.salud.gob.mx/.../30_guia_plastificada_iras_y_e... - Similar
Muriel Vasconcellos Mar 9, 2010:
Alternative options? Could it possibly be 'vial/ampoule' in the sense of 'either-or'? Lots of examples on the Internet with a "slash" (solidus). Otherwise, it's troubling to see the two terms together because they are clearly not the same thing.
On another note, I read an explanation that an ampoule is a kind of vial, like a narrower term from a broader category, but it was not a scientific reference, so I'm not going to cite it here.
liz askew Mar 9, 2010:
Yes, you can, 3 mL vial...plus the other references I quoted in my contribution. [PDF]
Interferon Beta-1b (Betaseron, Extavia)
File Format: PDF/Adobe Acrobat - Quick View
by C Policy - Related articles
(Human), USP, and 15 mg Mannitol, USP. Drug is packaged in a clear glass, single-use vial (3 mL capacity). A ... Extavia is supplied as a lyophilized powder containing 0.3 mg of Interferon beta-1b, 15 mg Albumin. (Human), USP, and 15 mg ...
www.cigna.com/.../ph_6007_coveragepositioncriteria_interfer... - Similar
Rita Tepper Mar 9, 2010:
El frasco ampolla puede tener 3 ml Laboratorio:PRODUCTOS FARMACEUTICOS DR.GRAY SACI

Forma: INYECTABLE
ATC:
Via: INTRAVENOSA
Venta: BAJO RECETA
Presentaciones:
FRASCO AMPOLLA-10 AMP/10ML
FRASCO AMPOLLA-50 FCO.AMP/20ML(UH)
FRASCO AMPOLLA-100 FCO.AMP/20ML(UH)
FRASCO AMPOLLA-5 FCO.AMP/50ML(UH)
FRASCO AMPOLLA-10FCO.AMP/50ML(UH)
FRASCO AMPOLLA-1FCO.AMP/100ML(UH)
FRASCO AMPOLLA-5FCO.AMP/100ML(UH)
FRASCO AMPOLLA-10FCO.AMP/100ML(UH)
FRASCO AMPOLLA-1 AMP/3 ML
FRASCO AMPOLLA-5 AMP/3ML
FRASCO AMPOLLA-10 AMP/3ML
FRASCO AMPOLLA-25 AMP/3ML (UH)
FRASCO AMPOLLA-50 AMP/3ML (UH)
FRASCO AMPOLLA-100 AMP/3ML (UH)
FRASCO AMPOLLA-1 AMP/10ML
FRASCO AMPOLLA-5 AMP/10ML
FRASCO AMPOLLA-25 AMP/10ML(UH)
FRASCO AMPOLLA-50 AMP/10ML(UH)
FRASCO AMPOLLA-100 AMP/10ML (UH)
FRASCO AMPOLLA-1 FCO.AMP/20ML
FRASCO AMPOLLA-5 FCO.AMP.20/ML
FRASCO AMPOLLA-10 FCO.AMP.20/ML
FRASCO AMPOLLA-25 FCO.AMP/20ML(UH)
FRASCO AMPOLLA-25FCO.AMP/100ML(UH)
FRASCO AMPOLLA-50FCO.AMP/100ML(UH)
FRASCO AMPOLLA-100FCO.AMP/100ML(UH)
FRASCO AMPOLLA-10 FCO.AMP/50ML(UH)
FRASCO AMPOLLA-25 FCO.AMP/50ML(UH)
FRASCO AMPOLLA-50 FCO.AMP/50ML(UH)
FRASCO AMPOLLA-100FCO.AMP/50ML(UH)
Principios activos:
PROPOFOL: 10.0 MG
Gloria Rivera Mar 9, 2010:
Liz... I have an idea.... I just noticed that this "frasco-ámpula" is 3ml. I have not been able to find a vial that can contain that little fluid. If my memory does not betray me, vials usually contain 10ml up. And what kills me is that I cannot research more since I have to leave my computer!
So, here are my 2 cents :)
liz askew Mar 9, 2010:
small, sealed glass container
English translation: phial7UK)/vial (US)/ ampoule/ampule


English term or phrase: small, sealed glass container
English translation: phial7UK)/vial (US)/ ampoule/ampule
Entered by: aceavila - Noni
Options:
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15:41 Feb 17, 2009
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English to English translations [Non-PRO]
Art/Literary - General / Conversation / Greetings / Letters
English term or phrase: small, sealed glass container
Taking a poll here:

What would you call a small, sealed glass container that looks like this:

http://www.buyemp.com/tmp_image.php?item_id=1123005&width=15...

Context: Work of fiction (screenplay). Contains a powerful (fictional) addictive narcotic.

I'm looking for the term that most people would understand, not necessarily the most "scientific" term. US English.

ntext
KudoZ activity
Questions: 179 (1 open)
(1 without valid answers)
(5 closed without grading)
Answers: 2988

United States

Local time: 01:10
phial
Explanation:
I was careful not to look at any other answers before looking at the link.

However, I wd agree with Dere
liz askew Mar 9, 2010:
Hi Gloria

Site Map - Johnsen and Jorgensen UK - Plastic, Glass, Bottles ...
Tubular Glass Vials Large Tubular Glass Injection Vials (Amber & clear Type I & III tubular glass vials) Screw Neck Tubular Glass Vials (Amber & Clear type ...
www.jjpack.com/sitemap.htm - Cached - Similar
Gloria Rivera Mar 9, 2010:
Hi guys... What makes me incline towards "ampoule" (and not only ´cause I proposed it) is the fact that vials usually come in "see through" glass containers and "ampoules" come in amber glass, just like the product description. "frasco-ámpula vidrio ambar"
Quoting Liz, tough call :)
liz askew Mar 9, 2010:
not exactly the same, but may help in this query.
liz askew Mar 9, 2010:
I have just found this: dose vial > frasco-ampolla de dosis única
- [ Translate this page ]
6 posts - 5 authors - Last post: 4 Jul 2006
dose vial. Spanish translation: frasco-ampolla de dosis única .... pero en inglés correspondería con "single-dose vial", que no es tu caso. ...
www.proz.com › ... › English to Spanish › Medical (general) - Cached - Similar
liz askew Mar 9, 2010:
What do they say in the US of A, "a tough call"??
David Brown Mar 9, 2010:
Vial The vials shown by Liz are indeed vials, but these are then bought by drug manufacturers to sterilise, add their compounds and then "seal" them
Constantinos Faridis (X) Mar 9, 2010:
Gloria Rivera Mar 9, 2010:
Hi! Do you have any pics? Because my first option was "vial" (David, great minds think alike), but then after reading the description, I remembered what we call "ampollas" in Perú and went for ampoule.

So, take a look at the pics, I think they are easier to understand than my explanation. (It´s way past my bedtime) :)
*www.isips.org/Safety_Ampoule_breaker.php ampoule (ampolla or "frasco-ámpula in this case)
* sealed vial: www.sani.com.ar/productos/fotos/4240.jpg
Saludos,
Gloria

Proposed translations

+1
3 hrs
Selected

vial

I think it is just "vial", why would it be sealed?

Internet
- [ Translate this page ]
Soluciones en frasco ampula (vial) en envase aséptico en las presentaciones de: 4, 5, 10, 20, 30, 58 y 60 ml. 9. Soluciones en frasco ampula (vial) en ...
www.safeph.com.mx/seccion.asp?it_id=200&sec_id...0... – Cached

Glycopyrrolate Injection USP 200 micrograms/ml, 1ml & 3ml ...
Glycopyrrolate Injection USP 200 micrograms/ml, 1ml & 3ml. Table of Contents. 1. NAME OF THE MEDICINAL PRODUCT; 2. QUALITATIVE AND QUANTITATIVE COMPOSITION ...
emc.medicines.org.uk/printfriendlydocument.aspx?documentid... - Cached
a
- [ Translate this page ]
VASOPRESINA U.S.P. 20 U/ml. Vasopresor. (Vasopresina). Inyectable. .... conteniendo 6 ampollas A por 2 mL de color ámbar transparente y 6 ... Inyectable, frasco ámpula 250 mg en polvo liofilizado, ampolla x 10 ml de solvente para reconstituir. .... Ampollas 75 mg/3 ml, caja x 5. Tabletas 75 mg, caja x 20. NOVARTIS. ...
www.drogassa.com.co/plm/orm/v.htm – Cached

Albuterol Sulfate Inhalation Solution, USP 0.083% - 3mL Vial ...
Manufacturer: Nephron Pharmaceutical Corp.; Product: Albuterol Sulfate Inhalation Solution, USP 0.083% - 3mL Vial; Category: Pharmaceuticals, Drug Vials; ...
www.dixieems.com/Albuterol-Sulfate-Inhalation-Solution-USP-... – Cached

Lyophilized Injection - Products for Lyophilized Injection ...
Ganciclovir for Injection Lyophilized Powder in Vial (50mg, 125mg, 250mg) Prevent CMV on transplant recipient with a high risk of CMV infection; ...
www.bikudo.com/product_list/.../Lyophilized_Injection.html - Cached – Similar


#
Injection Vial Manufacturers, Buyers & Suppliers - ECPlaza
Dosage Form: Injection. Indications: CMV retinitis. Description: Sterile lyophilized powder in strength of 500 mg or 250mg or 50mg per vial for intravenous ...
www.ecplaza.net › Buy Now - Cached - Similar
#
Orencia (abatacept) Dosage - Drugs.com
Each ORENCIA vial provides 250 mg of abatacept for administration. ... in each vial must be reconstituted with 10 mL of Sterile Water for Injection, USP, ... Upon complete dissolution of the lyophilized powder, the vial should be vented ...
www.drugs.com/dosage/orencia.html - Cached
# [PDF]
PRODUCT MONOGRAPH ORENCIA* (abatacept) Intravenous Injection 250 ...
File Format: PDF/Adobe Acrobat - View as HTML
by P ORENCIA - 2006 - Related articles
17 Feb 2010 ... ORENCIA (abatacept) lyophilized powder must be refrigerated at 2° to 8°C. Do not ... Abatacept for Injection, 250 mg/vial, is a lyophilized ...
www.bmscanada.ca/.../ORENCIA_E_PM_17 February 2010_APP_CLN....
# [PDF]
Code АТС Composition Dosage form Packing L ANTINEOPLASTIC AND ...

[PDF]
UMDNS English/Spanish 2007- Sorted by Codes 2006 New Terms: 1029 ...
File Format: PDF/Adobe Acrobat
Medios de Contraste, Radiográficos, Inyectables ...... Seal Decrimpers, Bottle/Vial. De-Plegadores para Sellaje, para Botelles/Frasquitos ...
www.minsa.gob.pa/.../2007 Spanish UMDNS.Codes.pdf - Similar


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Note added at 3 hrs (2010-03-09 10:22:15 GMT)
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p.s.

I am questioning "sealed" purely because it does not state "cerrado/sellado" in the original text.

I hope I haven't put my foot in it.

This is up for discussion.

--------------------------------------------------
Note added at 4 hrs (2010-03-09 10:24:13 GMT)
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njection glass vial - injection glass vial products manufacturers ...
3ml serum glass vial · 10 Similar. suitable for lyophilized preparation and .... Injection Vial (USP Type- III) Assorted vials in amber and clear glass: 5ML ...
www.alibaba.com/showroom/injection_glass_vial.html - Cached

--------------------------------------------------
Note added at 8 hrs (2010-03-09 15:05:42 GMT)
--------------------------------------------------

LA ESTABILIDAD DE LA INSULINA DESPUES DE LA APERTURA DEL FRASCO ...
- [ Translate this page ]
Los frascos-ampollas y los cartuchos de insulina traen la fecha de vencimiento, ... Menos conocido es el hecho de que, una vez que los frascos-ampollas o ...
www.siicsalud.com › ... › Expertos del Mundo - Cached – Similar

OH Diabetes Care Tips - Charts for insulin storage
The shelf-life and viability of insulin in varies according to type of insulin, the type of container it comes in (vial or cartridge) and how it is used ...
www.isletsofhope.com/diabetes/.../tips_insulin_chart_1.html - Cached - Similar


ultimately the choice is yours Joseph:)

--------------------------------------------------
Note added at 8 hrs (2010-03-09 15:08:52 GMT)
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Vacunas contra difteria, tosferina, tetanos, Haemophilus ...
- [ Translate this page ]
Durante la administración de una dosis proveniente de un frasco ámpula sellado herméticamente con un tapón de caucho, este tapón junto con el arillo ...
www.vacunasparatushijos.com/vacuna-contra-difteria-tosferin... - Cached - Similar

--------------------------------------------------
Note added at 10 hrs (2010-03-09 17:00:13 GMT)
--------------------------------------------------

#
DEFEROXAMINE MESYLATE injection, powder, lyophilized, for solution ...
3 DailyMed Drugs List. Inc.] DECCOX (decoquinate) granule [Alpharma Inc. Animal Health] ... Lyophilized powder is then sealed in a 5-mL vial under an argon ...
www.searchmedica.com/search.html?... powder, lyophilized... - United States - Cached
#
Concentrated, stabilized cis-diamminedinitratoplatinum solutions ...
by MA Kaplan - 1990 - Related articles
vial When reconstituted with 10 ml. of Sterile Water for Injection, USP, ... Caution The lyophilized dosage formulations contain no preservatives and therefore ... Slurry the crystals in 50 mL of methanol for 1 hour (any excess AgNO 3 ... and placed in amber vials which ar sealed with suitable rubber stoppers and ...
www.freepatentsonline.com/4946689.html

For the record.

I would not use "sealed" in my own personal translation.

Peer comment(s):

neutral David Brown : "frasco-ampula" menas just more than "vial" or just more than "ampoule", the author could have just used "frasco" or "ampula"
1 hr
I am 100% right.
agree Muriel Vasconcellos : In all the flurry, I had forgotten to agree with your answer.
2 days 21 mins
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Buenos días, Liz. Thanks for your help with this. A vial may well be sealed when it contains medication, but in and of itself it's simply a vial. "
6 mins

ampule bottle

ampules bottle manufacturers directory - over 3000000 registered importers and exporters. ampules bottle manufacturers, ampules bottle suppliers, ...
www.tradekey.com › Sell Offers - Προσωρινά αποθηκευμένηampoule type C bottle ampoule bottle,ampoule type C bottle,type C ... - [ Μετάφραση αυτής της σελίδας ]
Alibaba.com provides ampoule type C bottle, check ampoule type C bottle products detail: type C ampoule of horn-toppedglass: USP type I and IIColor: clear ...
www.alibaba.com › ... › Bottles - Προσωρινά αποθηκευμένη - ΠαρόμοιεςSHIP in a BOTTLE: medicine ampule - eBay (item 360240042224 end ... - [ Μετάφραση αυτής της σελίδας ]
4 Mar 2010 ... eBay: Find SHIP in a BOTTLE: medicine ampule in the Collectibles , Transportation , Boats Ships , Other category on eBay.
cgi.ebay.com/SHIP-in-a-BOTTLE:--medicine-ampule_W0QQitemZ360240042224QQcmdZVie... -
Ampule storage bag - Patent 6024221 - από S Yuyama - 2000 -
A combination of an ampule storage bag and a transfusion bottle, wherein: ..... To use each drug set comprising a drug bottle and ampules (or vials) stored ...
www.freepatentsonline.com/6024221.html
Note from asker:
Ciao Constantinos. Gracias por tu aporte, y estoy de acuerdo con Gloria: necesitas presentar con más cuidado tus ejemplos
Peer comment(s):

disagree Gloria Rivera : Hi Constantinos, I checked your links, but I don´t see anything related to the question. :(
29 mins
agree Patrick Weill
2562 days
Something went wrong...
34 mins

ampoule

I think this is what you are describing. In Perú (where I used to be an MD) they are called "ampollas".
I hope this helps,
Gloria

*Ampoules are small glass vessels in which liquids for injections are hermetically sealed. A typical pharmaceutical ampoule has a narrow neck between a cylindrical body and a conical tip.
http://www.isips.org/Safety_Ampoule_breaker.php

*"Each ampoule of 2ml contains Vitamin B12 (cyanocobalamin..."
http://www.lasca.com.py/en/products.php?prod=136
Note from asker:
Gracias Gloria, por tu respuesta.
Peer comment(s):

disagree David Brown : this would just be called "ampula", "ampolla" or "ampolleta"
5 mins
which is what I understand (as a native Spanish speaker) from "frasco ámpula" :)
agree liz askew : FWIW, I believe "ampoule/vial" are suitable here. [PDF] Fasturtec (rasburicase) File Format: PDF/Adobe Acrobat by P FASTURTEC - Related articles The drug product is a sterile, white to off-white, lyophilized powder intended for intravenous infusion follow
11 hrs
Something went wrong...
+1
34 mins

sealed vial

It is not an ampoule it is a bottle (or vial) with a rubber (for example) seal for adding or transferring by syringe
The sealed vial of powdered or lyophilized drug is then accessed with a needle and syringe to add the liquid diluent. The vial is shaken to mix the drug ...
www.patentstorm.us/patents/5466220/description.html

And fotos here..
http://enlaceveterinario.com.mx/products/imagenes de novarti...
The sealed vial of powdered or lyophilized drug is then accessed with a needle and syringe to add the liquid diluent. The vial is shaken to mix the drug ...
www.patentstorm.us/patents/5466220/description.html

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Note added at 38 mins (2010-03-09 07:01:54 GMT)
--------------------------------------------------

Another foto of a "sealed sterile vial"

http://www.finafast.com/products/Pre_Sealed_Sterile_Vial-33-...

--------------------------------------------------
Note added at 59 mins (2010-03-09 07:23:03 GMT)
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a definitive photo---

http://www.dipromed.com.mx/index/components/com_virtuemart/s...

--------------------------------------------------
Note added at 10 hrs (2010-03-09 16:51:00 GMT)
--------------------------------------------------


http://spanish.alibaba.com/product-cgs/tubular-glass-vial-in...

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Note added at 10 hrs (2010-03-09 17:03:35 GMT)
--------------------------------------------------

More wood for the fire....from SPCs of marketed drugs...

VISUDYNE 15 mg, powder for solution for infusion - Summary of ... - Shelf-life in the sealed vial: 4 years. Shelf-life after reconstitution and ...
emc.medicines.org.uk/document.aspx?documentId... - En caché - Similares
Amazon.com: Dermabond Topical Skin Adhesive .5ml (1 sealed vial ... - [Dermabond Topical Skin Adhesive .5ml (1 sealed vial): Everything Else. ... Product Features. - Dermabond, Wound Closure 2-Octyl Cyanoacrylate ...
www.amazon.com › Everything Else › General - En caché
[PDF] 1 ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - [ Traducir esta página ]Formato de archivo: PDF/Adobe Acrobat - Vista rápida
Shelf-life in the sealed vial: 2 years. Shelf-life after reconstitution and dilution: 4 hours ... Product Characteristics, Section 4.2). ...
ec.europa.eu/enterprise/sectors/pharmaceuticals/.../anx_3698_en.pdf

This is my last word on this topic...................
Note from asker:
And thanks very much for your contribution, David.
Peer comment(s):

neutral liz askew : now we are nit-picking. Why didn't the author put "sellado"?
8 hrs
agree Rita Tepper : All vials are sealed
9 hrs
Something went wrong...
15 hrs

vial

I have been working at a pharmaceutical company for over 5 years, and 99% of the times, vials are safely secured, sanitized and filled in clean hospitalized rooms, so there´s no need to include safe vials or secure vials, etc.
Note from asker:
Thank you, Olga, for your answer and comments also.
Something went wrong...

Reference comments

2 hrs
Reference:

Ampoule

From Wikipedia, the free encyclopedia
An ampoule (also ampule or ampulla) is a small sealed vial which is used to contain and preserve a sample, usually a solid or liquid. Ampoules are commonly made of glass, although plastic ampoules do exist.

Modern ampoules are most commonly used to contain pharmaceuticals and chemicals that must be protected from air and contaminants. They are hermetically sealed by melting the thin top with an open flame, and usually opened by snapping off the neck. If properly done, this last operation creates a clean break without any extra glass shards or slivers; but the liquid or solution may be filtered for greater assurance. The space above the chemical may be filled with an inert gas before sealing. The walls of glass ampoules are usually sufficiently strong to be brought into a glovebox without any difficulty.

Glass ampoules are more expensive than bottles and other simple containers, but there are many situations where their superior imperviousness to gases and liquids and all-glass interior surface are worth the extra cost. Examples of chemicals sold in ampoules are injectable pharmaceuticals, air-sensitive reagents like tetrakis(triphenylphosphine)palladium(0), hygroscopic materials like deuterated solvents and trifluoromethanesulfonic acid, and analytical standards.
Note from asker:
Hi Muriel ... thanks for this interesting and helpful information.
Something went wrong...
9 hrs
Reference:

See these images

Ampoule:
www.exchangesupplies.org/needle_exchange_supp...

Sealed vial
www.m-generic.net/.../m-amoxicilline.html




--------------------------------------------------
Note added at 9 horas (2010-03-09 16:11:06 GMT)
--------------------------------------------------

Y frasco ampolla
www.laboratoriosaviar.com/es/documentos/produ...


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Note added at 13 horas (2010-03-09 19:30:56 GMT)
--------------------------------------------------

Espero que puedan ver este link con imágenes ilustrativas donde se ve la diferencia entre una ampolla y un frasco ampolla:
http://www.taringa.net/posts/apuntes-y-monografias/3182666/a...
Note from asker:
Hi Rita. Thanks for your comments and input, which I always appreciate.
Peer comments on this reference comment:

neutral Gloria Rivera : Rita, I took a look at the links and they do not work :(
36 mins
Sorry Gloria, but if you type ampoule, sealed vial and frasco ampolla in google images you may find them.
Something went wrong...
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