Glossary entry

Portuguese term or phrase:

Filantostina

English translation:

phyllanthostatin

Added to glossary by Beatriz Baker Méio
May 20, 2015 19:00
8 yrs ago
Portuguese term

Filantostina

Portuguese to English Science Botany Plants
Das raízes de P. acuminatus foram isoladas diversas substâncias, entre elas as filantostatinas.
Change log

May 29, 2015 16:34: Beatriz Baker Méio Created KOG entry

Proposed translations

+1
18 mins
Selected

phyllantostatin

Pettit, G. R., Schaufelberger, D. E., Nieman, R. A., Dufresne, C. & Saenz-Renauld, J. A. (1990). Antineoplastic agents, 177. Isolation and structure of phyllantostatin 6. Journal of Natural Products . Vol. 53, No. 6
Reference from here http://cdn.intechweb.org/pdfs/24230.pdf
Peer comment(s):

neutral Muriel Vasconcellos : I tried that, but I couldn't find enough references because I was spelling it wrong.
6 mins
agree Patricia Fierro, M. Sc.
4 hrs
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4 KudoZ points awarded for this answer.
+3
26 mins

phyllanthostatin

Explanation:
http://en.wikipedia.org/wiki/Phyllanthus_acuminatus

Phyllanthus acuminatus, the Jamaican gooseberry tree, is a herb-like plant of the family Phyllanthaceae, found only in Central America and South America. This plant is used by the local population (the Choco) as a piscicide.
Medical interest
This species is known to contain antineoplastic glucosides, which makes it interesting in the treatment of melanoma. Moreover, **phyllanthosthatin** isolated from its root is found to inhibit the development of leukemia at laboratory mice.




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Note added at 23 mins (2015-05-20 19:23:57 GMT)
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**Phyllanthostatin** A | C29H30O13 - PubChem
pubchem.ncbi.nlm.nih.gov/compound/Phyllanthostatin_APubChem
Phyllanthostatin A | C29H30O13 | CID 128959 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ...
Isolation and structure of the cytostatic lignan glycoside ...

www.ncbi.nlm.nih.gov/...
National Center for Biotechnology Information
by GR Pettit - ‎1988 - ‎Cited by 28 - ‎Related articles
J Nat Prod. 1988 Nov-Dec;51(6):1104-12. Isolation and structure of the cytostatic lignan glycoside **phyllanthostatin A**. Pettit GR(1), Schaufelberger DE.

Antineoplastic Agents, 177. Isolation and Structure of ...
pubs.acs.org/doi/abs/10.1021/np50072a002
American Chemical Society
by GR Pettit - ‎1990 - ‎Cited by 55 - ‎Related articles
Isolation and Structure of **Phyllanthostatin** 6. George R. Pettit , Daniel E. Schaufel-berger , Ronald A. Nieman , Claude Dufresne , J. A. Saenz-Renauld. J. Nat.
Peer comment(s):

agree Beatriz Baker Méio : tem razão Muriel! Sempre ajuda partir do nome do gênero...
2 mins
Obrigada, Beatriz.
agree Rafael Sousa Brazlate : Nossa, que confusão esses hh, hehe... Parece que esta forma é a correta.
10 mins
Obrigada, Rafael.
agree Maria Teresa Borges de Almeida
18 mins
Thanks, Teresa!
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