Mar 13, 2019 20:45
5 yrs ago
3 viewers *
Spanish term
Netherlands
Broad medical experience
Native in: English (Variants: UK, US) 
Works in: Spanish to English, Portuguese to English
cuerpo central de la polimixina (colistina)
Spanish to English
Medical
Medical (general)
Fosfomycin
En el tratamiento de las infecciones intraabdominales y en las de piel y tejidos blandos causadas por enterobacterias productoras de carbapenemasas, las combinaciones dobles de tigeciclina con un carbapenem o un aminoglucósidos fueron las más comunes y en el caso de las infecciones de tracto urinario complicadas lo fue la asociación de un aminoglucósido con fosfomicina (34/105, 32,4%).
En el caso de infecciones causadas por P. aeruginosa con resistencia a carbapenémicos, el tratamiento combinado unió al cuerpo central de la polimixina (colistina) un carbapenem (54,7% en el caso de las bacteriemias), un aminoglucósido o fosfomicina.
I'm not sure what author is talking about with "central body of the polymyxin". I can't find Google results on this. Thoughts?
TIA,
Juliette
En el caso de infecciones causadas por P. aeruginosa con resistencia a carbapenémicos, el tratamiento combinado unió al cuerpo central de la polimixina (colistina) un carbapenem (54,7% en el caso de las bacteriemias), un aminoglucósido o fosfomicina.
I'm not sure what author is talking about with "central body of the polymyxin". I can't find Google results on this. Thoughts?
TIA,
Juliette
Proposed translations
(English)
| 4 | core regimen |
raptisi
|
Proposed translations
1 day 13 hrs
Selected
core regimen
It does not refer to the polymyxin molecule, as it would appear at a first glance.
Reference:
4 KudoZ points awarded for this answer.
Reference comments
3 hrs
Andres Larsen
Venezuela
Venezuela
Native in English
Venezuela
freelance translator
Native in: English 
Works in: Spanish to English, English to Spanish, German to English, and 3 more.
Related KudoZ points
:
126
Reference:
colistin (polymyxin E) / polymyxin E (colistin)
Treatment of sepsis: What is the antibiotic choice in bacteremia due to ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561501/ -
F Alhashem - 2017 -
Core tip: Carbapenem resistant Enterobacteriaceae (CRE) is the most ... infections, the central nervous system (CNS) and the cardiovascular system. ... followed by Pseudomonas infection, Enterobacteriaceae and fungal infection, respectively. .... e.g., polymyxin E (colistin), polymyxin B, aminoglycosides and fosfomycin, ...
Rational use of intravenous polymyxin B and colistin - Medical Journal ...
www.e-mjm.org/2018/v73n5/polymyxin-B-and-colistin.pdf
ZZ Deris - 2018 -
5 oct. 2018 - Polymyxin B and colistin (polymyxin E) are the only two polymyxins available for ... antibiotics, aminoglycosides.3 Interestingly, the clinical use of intravenous (IV) ..... symptoms.49 Sepsis markers e.g. procalcitonin are very helpful in decision making .... or fosfomycin with OR of 1.57 (95%CI : 1.06 to 2.32) for.
Polymyxin B: similarities to and differences from colistin (polymyxin E).
https://www.ncbi.nlm.nih.gov/pubmed/17914915
A Kwa - 2007 -
Expert Rev Anti Infect Ther. 2007 Oct;5(5):811-21. Polymyxin B: similarities to and differences from colistin (polymyxin E). Kwa A(1), Kasiakou SK, Tam VH, ...
Polymyxins: An overview - UpToDate
https://www.uptodate.com/contents/polymyxins-an-overview
G MacLaren -
Feb 7, 2018 - However, only polymyxin B and polymyxin E (also known as colistin) are in clinical use [1]. They were isolated from Paenibacillus polymyxa ...
--------------------------------------------------
Note added at 3 hrs (2019-03-14 00:38:12 GMT)
--------------------------------------------------
Polymyxin B and Colistin
med.stanford.edu/content/.../main/.../SMUG-PolymyxinB%20vs%20Colistin.pdf
What: Polymyxin B is preferred over Colistin (polymyxin E) for infections due to ... Colistin. Use ideal body weight. Doses expressed in colistin base activity. IV.
Clinical considerations for optimal use of the polymyxins: A focus on ...
https://www.clinicalmicrobiologyandinfection.com/article/S11...
JM Pogue - 2017 -
Feb 24, 2017 - Colistin (polymyxin E) and polymyxin B became commercially .... major approaches to colistin dosing; that of the US package insert .... determining colistin dose, the authors would recommend using ideal body weight or actual.
--------------------------------------------------
Note added at 3 hrs (2019-03-14 00:41:49 GMT)
--------------------------------------------------
Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are ...
https://www.researchgate.net/.../309304537_Pharmacokineticsp... -
The polymyxin antibiotics [colistin and polymyxin B (PMB)] are increasingly used ... as colistin (polymyxin E) is intravenously administered to patients in the form of an ..... The threat of colistin resistance among carbapenem-resistant Klebsiella ... A Whole‐Body Physiologically Based Pharmacokinetic Model for Colistin and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561501/ -
F Alhashem - 2017 -
Core tip: Carbapenem resistant Enterobacteriaceae (CRE) is the most ... infections, the central nervous system (CNS) and the cardiovascular system. ... followed by Pseudomonas infection, Enterobacteriaceae and fungal infection, respectively. .... e.g., polymyxin E (colistin), polymyxin B, aminoglycosides and fosfomycin, ...
Rational use of intravenous polymyxin B and colistin - Medical Journal ...
www.e-mjm.org/2018/v73n5/polymyxin-B-and-colistin.pdf
ZZ Deris - 2018 -
5 oct. 2018 - Polymyxin B and colistin (polymyxin E) are the only two polymyxins available for ... antibiotics, aminoglycosides.3 Interestingly, the clinical use of intravenous (IV) ..... symptoms.49 Sepsis markers e.g. procalcitonin are very helpful in decision making .... or fosfomycin with OR of 1.57 (95%CI : 1.06 to 2.32) for.
Polymyxin B: similarities to and differences from colistin (polymyxin E).
https://www.ncbi.nlm.nih.gov/pubmed/17914915
A Kwa - 2007 -
Expert Rev Anti Infect Ther. 2007 Oct;5(5):811-21. Polymyxin B: similarities to and differences from colistin (polymyxin E). Kwa A(1), Kasiakou SK, Tam VH, ...
Polymyxins: An overview - UpToDate
https://www.uptodate.com/contents/polymyxins-an-overview
G MacLaren -
Feb 7, 2018 - However, only polymyxin B and polymyxin E (also known as colistin) are in clinical use [1]. They were isolated from Paenibacillus polymyxa ...
--------------------------------------------------
Note added at 3 hrs (2019-03-14 00:38:12 GMT)
--------------------------------------------------
Polymyxin B and Colistin
med.stanford.edu/content/.../main/.../SMUG-PolymyxinB%20vs%20Colistin.pdf
What: Polymyxin B is preferred over Colistin (polymyxin E) for infections due to ... Colistin. Use ideal body weight. Doses expressed in colistin base activity. IV.
Clinical considerations for optimal use of the polymyxins: A focus on ...
https://www.clinicalmicrobiologyandinfection.com/article/S11...
JM Pogue - 2017 -
Feb 24, 2017 - Colistin (polymyxin E) and polymyxin B became commercially .... major approaches to colistin dosing; that of the US package insert .... determining colistin dose, the authors would recommend using ideal body weight or actual.
--------------------------------------------------
Note added at 3 hrs (2019-03-14 00:41:49 GMT)
--------------------------------------------------
Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are ...
https://www.researchgate.net/.../309304537_Pharmacokineticsp... -
The polymyxin antibiotics [colistin and polymyxin B (PMB)] are increasingly used ... as colistin (polymyxin E) is intravenously administered to patients in the form of an ..... The threat of colistin resistance among carbapenem-resistant Klebsiella ... A Whole‐Body Physiologically Based Pharmacokinetic Model for Colistin and ...
Discussion