Jan 12, 2022 15:23
2 yrs ago
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English term
Each word needs thorough attention.
Native in: Russian 
Works in: English to Russian, Russian to English, German to Russian, and 1 more.
HR
English to Russian
Medical
Medical (general)
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Main focus for X (компания) has shifted from RR to FL with the GMMG-HD7 results, and experts see this study confirming the need of quadruplets upfront. Results of GMMG-HD7, with MRD as a co-primary endpoint, show the highest MRD negativity rate after induction in TE NDMM. However, due to study design of duo primary endpoints, X cannot file for regulatory approval until the other co-primary endpoint (PFS after 2nd randomization) is met.
X continues to differentiate focusing on high unmet need subgroups for RR, including HR with gain 1q abnormality.
Во фразе " including HR" - HR - high risk или hazard ratio?
Спасибо.
Main focus for X (компания) has shifted from RR to FL with the GMMG-HD7 results, and experts see this study confirming the need of quadruplets upfront. Results of GMMG-HD7, with MRD as a co-primary endpoint, show the highest MRD negativity rate after induction in TE NDMM. However, due to study design of duo primary endpoints, X cannot file for regulatory approval until the other co-primary endpoint (PFS after 2nd randomization) is met.
X continues to differentiate focusing on high unmet need subgroups for RR, including HR with gain 1q abnormality.
Во фразе " including HR" - HR - high risk или hazard ratio?
Спасибо.
Proposed translations
(Russian)
| 4 | high-risk |
hawkwind
|
| 4 +1 | hazard ratio |
interprivate
|
Change log
Jan 12, 2022 15:23: changed "Kudoz queue" from "In queue" to "Public"
Proposed translations
8 hrs
Selected
high-risk
https://pubmed.ncbi.nlm.nih.gov/32750129/
A gain in 1q was found in 391 patients (28%) and was associated with anemia, hypercalcemia, high tumor burden, International Staging System (ISS) stage 3, high-risk (HR) translocations, and chromosome 13 abnormalities.
There is an unmet treatment need, particularly among patients with poor prognoses,
including those with high-risk cytogenetics,
A gain in 1q was found in 391 patients (28%) and was associated with anemia, hypercalcemia, high tumor burden, International Staging System (ISS) stage 3, high-risk (HR) translocations, and chromosome 13 abnormalities.
There is an unmet treatment need, particularly among patients with poor prognoses,
including those with high-risk cytogenetics,
4 KudoZ points awarded for this answer.
Comment: "Благодарю."
+1
1 hr
interprivate
Native in Russian
Native in: Russian 
, Ukrainian
Works in: English to Russian, Italian to Russian, Russian to English, and 1 more.
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243
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