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Jan 2 14:23
4 mos ago
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English term
the oxycodone prime-induced reinstatement test session
English to Russian
Science
Medical: Pharmaceuticals
синдром отмены�
FIG. 4A is a graph showing the mean number of active lever presses during ***the oxycodone prime-induced reinstatement test session*** as a function of tezampanel dose.
Conditions during prime reinstatement testing were identical to those during extinction except that either 3 or 10 mg/kg Tezampanel or its vehicle was administered 30 min prior to the reinstatement test session.
Additionally, 0.1 mg/kg s.c. oxycodone was administered 10 min prior to the reinstatement test session (i.e., oxycodone prime).
Conditions during prime reinstatement testing were identical to those during extinction except that either 3 or 10 mg/kg Tezampanel or its vehicle was administered 30 min prior to the reinstatement test session.
Additionally, 0.1 mg/kg s.c. oxycodone was administered 10 min prior to the reinstatement test session (i.e., oxycodone prime).
References
| anything here? |
liz askew
|
Reference comments
1 hr
Reference:
anything here?
https://www.issup.net/ru/knowledge-share/research/2018-02/iz...
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Note added at 2 godz. (2024-01-02 16:25:32 GMT)
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https://www.jove.com/t/2265/a-procedure-for-studying-footsho...
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Note added at 2 godz. (2024-01-02 16:30:09 GMT)
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I have had a good search but have found nothing in Russian for "reinstatement" but i did find a definition of the term
Reinstatement
The term “reinstatement” is used to describe the ability of a discrete CS, drug stimulus, or stressful stimulus to reinitiate responding, while “renewal” is preferred when referring to the ability of a contextual cue to reinitiate responding.
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Note added at 2 godz. (2024-01-02 16:30:19 GMT)
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https://www.sciencedirect.com/topics/psychology/reinstatemen...
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Note added at 2 godz. (2024-01-02 16:33:27 GMT)
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=
return to drug-seeking behaviour??
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Note added at 2 godz. (2024-01-02 16:38:10 GMT)
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i.e. resumption
this is an extremely difficult one!
I have failed to find much on any bilingual site.
Good luck in your quest!
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Note added at 2 godz. (2024-01-02 16:39:13 GMT)
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"Whereas the role of drug-related stimuli in motivating the resumption of drug use is not fully understood, such learned responses may be among the most important factors responsible for the high rates of relapse associated with cocaine and other drug addiction"
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Note added at 2 godz. (2024-01-02 17:00:40 GMT)
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p.s.
I see my very first reference uses "восстановление"
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Note added at 2 godz. (2024-01-02 17:03:35 GMT)
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770775/
***** Drug-priming-induced reinstatement: laboratory animals are first trained to self-administer a drug; typically each
drug delivery is paired with a discrete cue. Lever pressing is then extinguished in the presence of the discrete cue.****
During reinstatement testing under extinction conditions (typically in the presence of the discrete cue), pre-session
non-contingent priming injections of the previously self-administered drug or related drugs reinstate lever
responding.
Reinstatement model: An animal model of drug relapse in which laboratory animals are tested for reinstatement
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:25:32 GMT)
--------------------------------------------------
https://www.jove.com/t/2265/a-procedure-for-studying-footsho...
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:30:09 GMT)
--------------------------------------------------
I have had a good search but have found nothing in Russian for "reinstatement" but i did find a definition of the term
Reinstatement
The term “reinstatement” is used to describe the ability of a discrete CS, drug stimulus, or stressful stimulus to reinitiate responding, while “renewal” is preferred when referring to the ability of a contextual cue to reinitiate responding.
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:30:19 GMT)
--------------------------------------------------
https://www.sciencedirect.com/topics/psychology/reinstatemen...
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:33:27 GMT)
--------------------------------------------------
=
return to drug-seeking behaviour??
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:38:10 GMT)
--------------------------------------------------
i.e. resumption
this is an extremely difficult one!
I have failed to find much on any bilingual site.
Good luck in your quest!
--------------------------------------------------
Note added at 2 godz. (2024-01-02 16:39:13 GMT)
--------------------------------------------------
"Whereas the role of drug-related stimuli in motivating the resumption of drug use is not fully understood, such learned responses may be among the most important factors responsible for the high rates of relapse associated with cocaine and other drug addiction"
--------------------------------------------------
Note added at 2 godz. (2024-01-02 17:00:40 GMT)
--------------------------------------------------
p.s.
I see my very first reference uses "восстановление"
--------------------------------------------------
Note added at 2 godz. (2024-01-02 17:03:35 GMT)
--------------------------------------------------
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770775/
***** Drug-priming-induced reinstatement: laboratory animals are first trained to self-administer a drug; typically each
drug delivery is paired with a discrete cue. Lever pressing is then extinguished in the presence of the discrete cue.****
During reinstatement testing under extinction conditions (typically in the presence of the discrete cue), pre-session
non-contingent priming injections of the previously self-administered drug or related drugs reinstate lever
responding.
Reinstatement model: An animal model of drug relapse in which laboratory animals are tested for reinstatement
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