Glossary entry (derived from question below)
French term or phrase:
prélèvement PK
English translation:
PK sampling
Added to glossary by
Nigel Wheatley
Jan 25, 2012 21:02
12 yrs ago
33 viewers *
French term
prélèvement PK
French to English
Medical
Medical (general)
tests
This appears in a list of tests that will be carried out on patients in a clinical trial for a new drug to treat multiple myeloma. There no other 'context' to speak of, and I can't find anything that matches in the rest of the PIS.
PK can mean "protein kinase", but I can't see how that fits here. All suggestions are welcome!
PK can mean "protein kinase", but I can't see how that fits here. All suggestions are welcome!
Proposed translations
(English)
| 3 +7 | PK sampling |
Isabelle Berquin
|
| 4 | pyruvate kinase |
Jessie Nelson
|
| 3 | typo for BK? sampling/screening for BK |
Drmanu49
|
References
| Pharmacokinetics |
Sean Sheahan
|
Proposed translations
+7
20 mins
Isabelle Berquin
Native in French
Specializes in field
PhD with a solid scientific background
Native in: French (Variants: Standard-France, Belgian) 
Works in: English to French, French to English
Related KudoZ points
:
48
Selected
PK sampling
This could be the EN abbreviation for 'pharmacokinetic' - pharmacocinétique in FR. Additional samplings of blood, urine and possibly other samples are necessary to determine the fate of the drug in the body (absorption, distribution, metabolism, excretion...). It would seem to make sense in the context of a clinical trial for a new drug.
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Note added at 25 mins (2012-01-25 21:27:41 GMT)
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Some references:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01359...
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01445...
Optimal population designs for PK models with serial sampling. http://www.ncbi.nlm.nih.gov/pubmed/15702610
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Note added at 25 mins (2012-01-25 21:27:41 GMT)
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Some references:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01359...
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01445...
Optimal population designs for PK models with serial sampling. http://www.ncbi.nlm.nih.gov/pubmed/15702610
Note from asker:
| Indeed, that would make very good sense, thanks! :) |
4 KudoZ points awarded for this answer.
Comment: "Agree, almost a "kick myself" moment ;) Thanks for resolving my inspiration failure"
10 mins
typo for BK? sampling/screening for BK
web5.unilim.fr/cr_amylose_al/spip.php?rubrique86
Le plus souvent cette production se fait dans le cadre d'un myélome de stade I ou ..... et qu'elle est susceptible de contaminer les prélèvements faits par cytaphérèse. ...... Arendt BK, Ahmann GJ, Fonseca R, Mulvihill EM, Dispenzieri, A. Sikkink.
www.centres-pharmacovigilance.net/.../bulletin_crpv_fw_N10....
Format de fichier: PDF/Adobe Acrobat
multiple chez les patients non traités inéligibles à la chimiothérapie à haute dose avec ... mofetil, sirolimus : Concernant les néphropathies associées au BK et les .... myélome multiple traité par thalidomide ou lénalidomide en association avec ...
jvi.asm.org/content/84/4/2150.full - Traduire cette page
de E Bernhoff - 2010 - Cité 11 fois - Autres articles
Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells ▿ ..... induces apoptosis and diminishes proliferation of multiple myeloma cells.
Critical Care | Full text | Clinical review: Specific aspects of ...
ccforum.com/content/10/2/211 - Traduire cette page
de M Darmon - 2006 - Cité 26 fois - Autres articles
11 Apr 2006 – Several factors may cause renal failure in myeloma patients, with cast .... The well-documented association between the BK virus and ...
Le plus souvent cette production se fait dans le cadre d'un myélome de stade I ou ..... et qu'elle est susceptible de contaminer les prélèvements faits par cytaphérèse. ...... Arendt BK, Ahmann GJ, Fonseca R, Mulvihill EM, Dispenzieri, A. Sikkink.
www.centres-pharmacovigilance.net/.../bulletin_crpv_fw_N10....
Format de fichier: PDF/Adobe Acrobat
multiple chez les patients non traités inéligibles à la chimiothérapie à haute dose avec ... mofetil, sirolimus : Concernant les néphropathies associées au BK et les .... myélome multiple traité par thalidomide ou lénalidomide en association avec ...
jvi.asm.org/content/84/4/2150.full - Traduire cette page
de E Bernhoff - 2010 - Cité 11 fois - Autres articles
Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells ▿ ..... induces apoptosis and diminishes proliferation of multiple myeloma cells.
Critical Care | Full text | Clinical review: Specific aspects of ...
ccforum.com/content/10/2/211 - Traduire cette page
de M Darmon - 2006 - Cité 26 fois - Autres articles
11 Apr 2006 – Several factors may cause renal failure in myeloma patients, with cast .... The well-documented association between the BK virus and ...
1 hr
Jessie Nelson
United States
United States
Native in English
Specializes in field
United States
Communicate, grow the world.
Native in: English (Variant: US)
Works in: French to English
pyruvate kinase
According to the Dictionary of Medicine of Svetolik P. Djordjević revised edition 2004, PK stands for "pyruvate kinase-Internal Medicine and Laboratory". pg 653.
I tried a Google search for "pyruvate kinase and myeloma". There is a connection, but the articles exceed my ability to understand. You may have better luck.
I tried a Google search for "pyruvate kinase and myeloma". There is a connection, but the articles exceed my ability to understand. You may have better luck.
Reference comments
30 mins
Sean Sheahan
France
France
Native in English
Specializes in field
France
'In other words'
Native in: English
Works in: English to French, French to English, Irish to English
Reference:
Pharmacokinetics
The reference speaks for itself...
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